Practitioner's Guide to Designer Drugs

Overall, this catagory has the least number of currently known compounds. This is due to the fact that the "fan base" of these particular drugs is rather small compared to other substances. Because of that fact, these drugs have a tendency to fly under the regulatory radar longer before being banned.

 

A. Methoxetamine (MXE, 3-MeO-2-Oxo-PCE) - Active at 5mg. Illegal in Europe, but still technically legal in the US. Majority was manufactured in Europe and exported, so supply has dried up for the most part in the continental USA.

B. Diphenidine ((±)-1-(1,2-Diphenylethyl)piperidine) - active at 60mg intranasal

1. Methoxphenidine (MXP, 2-MeO-Diphenidine) - active at 60mg
 

C. Ketamine analogues

1. 2-MeO-Ketamine (2-(2-Methoxyphenyl)-2-(methylamino)cyclohexanone) - active at 50mg.

2. N-Ethyl-Norketamine (NEK, ethketamine, 2-(2-chlorophenyl)-N-(ethylamino)cyclohexanone) - active at 50mg.

D. PCP analogues

1. 3-MeO-PCP (3-methoxy-phencyclidine, 1-[1-(3-methoxyphenyl)cyclohexyl]-piperidine) - active at 10mg sublingual.

2. 4-MeO-PCP (4-methoxy-phencyclidine, 1-[1-(4-methoxyphenyl)cyclohexyl]-piperidine) - active at 25mg. impure, sloppy synthesis can produce very dangerous byproducts.

E. Tiletamine - responsible for several deaths in combination with zolazepam. Often abused as Telazol, a veterinary anesthetic which is 1:1 parts tiletamine/zolazepam.

F. Dizocilpine (MK-801) - One fatality involving MK-801, Benzodiazepines, and Alcohol.